DE-MRI Shows Which Myocardial Injury Is Irreversible
Delayed-enhancement MRI (DE-MRI) shows promise as a predictor of cardiac transplantation and all-cause mortality in the largest trial to assess the prognostic value of DE-MRI-identified myocardial scarring over a relatively long follow-up [1]. A review of 857 consecutive patients undergoing DE-MRI at St Luke’s Episcopal Hospital by Dr Benjamin Cheong (Baylor College of Medicine, Houston, TX) and colleagues found that myocardial fibrosis, which appears enhanced in MRI images about 15 minutes after the patient is given a dose of gadolinium chelate, correlates to worse odds of transplant-free survival. Results of the study were published online November 9, 2009 in Circulation.
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